SubtiBank SubtiBank
ywdH [2019-08-12 12:24:44]
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ywdH [2019-08-12 12:24:44]

similar to aldehyde dehydrogenase
locus
BSU_37960
pI
9.62
mw
50.60 kDa
protein length
457 aa Sequence Blast
gene length
1371 bp Sequence Blast
function
unknown
product
unknown
essential
no
ec
1.2.1.3
synonyms
ipa-58r
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

    • Gene

    Coordinates
    3,896,290 → 3,897,660

    The protein

    Catalyzed reaction/ biological activity

  • aldehyde + H2O + NAD+ --> carboxylate + 2 H+ + NADH (according to UniProt)

    • Protein family

  • [SW|aldehyde dehydrogenase family] (according to UniProt)

    • Paralogous protein(s)

  • [protein|A0BEB92D54799956A4ADE106A1388E5710141069|GabD], [protein|EF0AAAF5BAE8E1F54FCA296643F7B9E3CE257B1D|YfmT], [protein|F3341F205CB939498109D2A54DE842065C488DD5|AldX], [protein|F9CF067A2A8E3B2BACC6A51A0E87E84640349980|AldY], [protein|1ADC55F8E265AF86E29743C671CE1EA1BE7EB41E|GbsA], [protein|2042F691CB37B1BAFE2CF3906A9F7F47457C3995|PutC], [protein|5B66ADB81AB141982F187B1C5E3A9346AA064DE2|YcbD], [protein|67A72A0EABCD807C25D8EAC61C251142B45C174E|DhaS], [protein|69838717DC6BB27864D88C282BF5BC7CC558BFD7|RocA], [protein|762718A15E5256261D79DF60F9106AF0CE2D60C6|IolA]

    • Structure

  • [PDB|3RHH] (from from ''Bacillus halodurans'' C-125 complexed with NADP, 28% identity, 62% similarity)

    • Expression and Regulation

    Operons

    genes
    [gene|99F1FAF28FB4817D94E84BD5288FA33124558933|ywdH]
    description
    [Pubmed|9353933]
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    Biological materials

    Mutant

  • MGNA-A564 (ywdH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/564 NBRP B. subtilis, Japan]
  • BKE37960 (Δ[gene|99F1FAF28FB4817D94E84BD5288FA33124558933|ywdH]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE37960 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCCGTTTCTCCTTTTTG, downstream forward: _UP4_TAAAAAAGCGCAGATCACCT
  • BKK37960 (Δ[gene|99F1FAF28FB4817D94E84BD5288FA33124558933|ywdH]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK37960 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCCGTTTCTCCTTTTTG, downstream forward: _UP4_TAAAAAAGCGCAGATCACCT

    • References

  • 9353933